Below are several examples of images acquired using MRI and PET some used in peer reviewed publications spanning fields of research in oncology, neurology and cardiology.
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ANTIGEN-LOADED DENDRITIC CELL MIGRATION: MR IMAGING INA PANCREATIC CARCINOMA MODEL.
Antigen-loaded dendritic cell migration: MR imaging in a pancreatic carcinoma model.Zhang Z, Li W, Procissi D, Li K, Sheu AY, Gordon AC, Guo Y, Khazaie K, Huan Y, Han G, Larson AC.
Radiology. 2015 Jan;274(1):192-200. doi: 10.1148/radiol.14132172. Epub 2014 Sep 15.
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ABERRANT RESTING STATE CONNECTIVITY IN A MODEL OF MAJOR DEPRESSION DISORDER (MRI)
Aberrant resting-state functional connectivity in a genetic rat model of depression. Williams KA, Mehta NS, Redei EE, Wang L, Procissi D. Psychiatry Res. 2014 Apr 30
IMAGE GUIDED NANOTHERAPIES
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Image-guided local delivery strategies enhance therapeutic nanoparticle uptake in solid tumors.
Mouli SK, Tyler P, McDevitt JL, Eifler AC, Guo Y, Nicolai J, Lewandowski RJ, Li W, Procissi D, Ryu RK, Wang YA, Salem R, Larson AC, Omary RA.
ACS Nano. 2013 Sep 24
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High Resolution 3D Rabbit Brain (rendering)
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RESTING STATE FMRI AND PAIN
Role of nucleus accumbens in neuropathic pain: linked multi-scale evidence in the rat transitioning to neuropathic pain.
Chang PC, Pollema-Mays SL, Centeno MV, Procissi D, Contini M, Baria AT, Martina M, Apkarian AV.
Pain. 2014 JUNE
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MULTIMODALITY CANCER STUDIES FOR THERAPEUTIC RESPONSE (PET AND MRI)
Serial diffusion MRI to monitor and model treatment response of the targeted nanotherapy CRLX101.Ng TS, Wert D, Sohi H, Procissi D, Colcher D, Raubitschek AA, Jacobs RE.Clin Cancer Res. 2013 May
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MOUSE GLIOMA IMAGING IN 3D
– 3D rendering of detected tumors
– Automated segmentation of tumors
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BRAIN TUMOR DYNAMIC CONTRAST ENHANCED IMAGING IN MICE
Regional uptake of Magnevist (Gd) in different regions reflects vascular permeability and cellular status
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REAL TIME CARDIAC IMAGING (MOUSE)
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DYNAMIC CONTRAST ENHANCED (Gaudolinium) IN KIDNEYS
Mouse is scanned in MRI and contrast agent injection occurs during image acquisition. Notice sudden enhancement of kidneys as contrast agent (Magnevist, Gd) arrives to the tissue.
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CANCER IMAGING – FLY-THROUGH OF RAT TUMOR (HCC) IMAGES
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DYNAMIC EYE MOVEMENT OF AWAKE RABBIT BY MRI
The movie shows real time MR images of an awake rabbit being scanned in the MRI. One can note the movement of the rapid movement of the eyes (NOTE: at a certain point Gd agent was injected through ear vein catether)
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DYNAMIC PET IMAGING (FDG UPATKE IN MOUSE)
PET images at different times post injection of 18F-FDG via tail vein catheter while in scanner
